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师资队伍
郑丽芳
职务/职称:副教授/硕导
研 究 所:药物化学研究所
联系电话:
电子邮件:zhenglf@lzu.edu.cn
办 公 室:勤博楼2023室
  • 个人简介
  • 研究成果
  • 研究项目
  • 【基本情况】
        2002年毕业于兰州大学化学化工学院,2007年获兰州大学有机化学博士学位,2014年~2015年在英国谢菲尔德大学化学系做访问学者。
    【研究方向】
        抗肿瘤靶标药物合成和活性研究
    【主讲课程】
        《分析化学》
    【获奖情况】

  • [1] Zhang L, He D, Li K, Wang B, Zheng L*, Li J, Emodin targets mitochondrial cyclophilin D to induce apoptosis in HepG2 cells. Biomedicine & Pharmacotherapy. 2017, 90: 222–228 

    [2] Li J, He D, Wang B, Zhang L, Li K, Xie Q, Zheng L*, Synthesis of hydroxycinnamic acid derivatives as mitochondria-targeted antioxidants and cytotoxic agents. Acta Pharmaceutica Sinica B, 2017,7: 106-115. 

    [3] Bao YF, Li JY, Zheng LF *, Li HY.; Antioxidant activities of cold-nature Tibetan herbs aresignifcantly greater than hot-nature ones and are associatedwith their levels of total phenolic components. Chinese Journal of Natural Medicines, 2015, 13: 609-617. 

    [4] Yin F, Wu Z, Zheng L*, Stability, cytotoxicity, and saturation effect of the free radical-scavengingcinnamic acid - dopaminehybrid antioxidants. Journal of Chinese Pharmaceutical Sciences, 2015, 24: 148–155. 

    [5] Wu Z, Zheng L, Li Y, et al, Synthesis and structure–activity relationships of phenylpropanoid amides of octopamine and dopamine on tyrosinase inhibition and antioxidation. Food chemistry. 2012, 134: 1128-1131 

    [6] Zheng LF, Dai F, Zhou B, et al, Prooxidant activity of hydroxycinnamic acids on DNA damage in the presence of Cu (II) ions:  Mechanism and structure-activity relationship. Food and Chemical Toxicology. 2008, 46: 149-156 

    [7] Zheng L, Wei Q, Zhou B, et al, Synthesis of 1,1,2-triphenylethylenes and their antiproliferative effect on human cancer cell lines. Anti-cancer drugs. 2007, 18: 1039-1044 

    [8] Zheng LF, Wei QY, Cai YJ, et al, DNA damage induced by resveratrol and its synthetic analogues in the presence of Cu (II) ions: Mechanism and structure-activity relationship. Free Radical Biology and Medicine. 2006, 41: 1807-1816  


  • 【1】 国家自然科学基金青年项目(21302079):以线粒体为作用靶点的羟基肉桂酸类生物抗氧化剂的设计、合成和生物活性研究,负责人。 

    【2】 甘肃省自然科学基金青年项目(1208RJYA014):青海产藏药阴阳属性与抗氧化活性相关性的实验研究,负责人


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